Searchable abstracts of presentations at key conferences in endocrinology

ea0070aep382 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

Different effects of 5α-dihydrotestosterone treatment on hepatic and visceral adipose tissue inflammation in animal model of polycystic ovary syndrome

Vojnovic Milutinovic Danijela , Velickovic Natasa , Nikolic Marina , Djordjevic Ana , Brkljacic Jelena , Teofilovic Ana , Bursac Biljana , Jelaca Sanja , Macut Djuro

Polycystic ovary syndrome (PCOS) is a complex reproductive disorder that is usually associated with metabolic disturbances such as obesity, dyslipidemia and insulin resistance. In this study, female rats treated with nonaromatizable 5α dihydrotestosterone (DHT) were used as an animal model of PCOS. The aim of this study was to assess the presence of inflammation in liver and visceral adipose tissue (VAT), which accompanies metabolic disturbances in animal model of PCOS. F...

ea0070aep435 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

Fructose-induced alterations of hepatic lipid metabolism are modulated by chronic stress in male rats

Velickovic Natasa , Vojnovic Milutinovic Danijela , Brkljacic Jelena , Teofilovic Ana , Bursac Biljana , Nikolic Marina , Gligororovska Ljupka , Kovacevic Sanja , Djordjevic Ana , Preitner Frédéric , Tappy Luc , Matic Gordana

Overconsumption of fructoseenriched beverages and everyday stress are both involved in the pathogenesis of metabolic disorders through their effects on hepatic lipid metabolism. The aim of this study was to investigate whether highfructose diet and chronic stress synergistically perturbs lipid metabolism in rat liver. Therefore, we analyzed the effects of 9-week 20% liquid fructose diet and 4-week chronic unpredictable stress, separately and in combination, on dyslipidemia, VL...